Antineoplastic Effect of a Combined Mitotane Treatment/Ionizing Radiation in Adrenocortical Carcinoma: A Preclinical Study

Mitotane (MTT) is an adrenolytic drug used in adjuvant and advanced treatments of adrenocortical carcinoma (ACC). Ionizing radiation (IR) is also used in adrenal cancer treatment, even though its biological action remains unknown. To provide a reliable in vivo preclinical model of ACC, we used mouse...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Cerquetti, Lidia, Bucci, Barbara, Carpinelli, Giulia, Lardo, Pina, Proietti, Antonella, Saporito, Raffaele, Rindi, Guido, Petrangeli, Elisa, Toscano, Vincenzo, Stigliano, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895792/
https://ncbi.nlm.nih.gov/pubmed/31717612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111768
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