Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer

Resistance to tamoxifen is a clinically major challenge in breast cancer treatment. Although downregulation of estrogen receptor‐alpha (ERα) is the dominant mechanism of tamoxifen resistance, the reason for ERα decrease during tamoxifen therapy remains elusive. Herein, we reported that Spalt‐like tr...

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Publicado no:EMBO Mol Med
Main Authors: Ye, Liping, Lin, Chuyong, Wang, Xi, Li, Qiji, Li, Yue, Wang, Meng, Zhao, Zekun, Wu, Xianqiu, Shi, Dongni, Xiao, Yunyun, Ren, Liangliang, Jian, Yunting, Yang, Meisongzhu, Ou, Ruizhang, Deng, Guangzheng, Ouyang, Ying, Chen, Xiangfu, Li, Jun, Song, Libing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895605/
https://ncbi.nlm.nih.gov/pubmed/31657150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910638
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