Intra-articular injection of etoricoxib-loaded PLGA-PEG-PLGA triblock copolymeric nanoparticles attenuates osteoarthritis progression

The current pharmacological therapies for osteoarthritis (OA) are mainly focused on symptomatic relief of pain and inflammation through the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Etoricoxib is a cyclooxygenase-2 (COX-2) selective NSAID with a higher cyclooxygenase-1 (COX-1) to COX-2 s...

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Publicat a:Am J Transl Res
Autors principals: Liu, Pingju, Gu, Liling, Ren, Lingyan, Chen, Jiajia, Li, Tao, Wang, Xin, Yang, Junjun, Chen, Cheng, Sun, Li
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895527/
https://ncbi.nlm.nih.gov/pubmed/31814887
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