Disulfiram combined with copper induces immunosuppression via PD-L1 stabilization in hepatocellular carcinoma

As a potential antitumor drug and chemotherapeutic sensitizer, disulfiram combined with Copper (DSF/Cu(2+)) does not exert considerable antitumor effects on an immunocompetent hepatocellular carcinoma (HCC) model. In this article, we will explore the mechanism underlying the resistance to DSF in HCC...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Zhou, Binghai, Guo, Lei, Zhang, Bo, Liu, Shuang, Zhang, Kewei, Yan, Jiuliang, Zhang, Wentao, Yu, Mincheng, Chen, Zheng, Xu, Yongfeng, Xiao, Yongsheng, Zhou, Jian, Fan, Jia, Li, Hui, Ye, Qinghai
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895448/
https://ncbi.nlm.nih.gov/pubmed/31815045
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