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Pum2 shapes the transcriptome in developing axons through retention of target mRNAs in the cell body

Localized protein synthesis is fundamental for neuronal development, maintenance, and function. Transcriptomes in axons and soma are distinct but the mechanisms governing the composition of axonal transcriptomes and their developmental regulation are only partially understood. We found that the bind...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Martínez, José C., Randolph, Lisa K., Iascone, Daniel Maxim, Pernice, Helena F., Polleux, Franck, Hengst, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895424/
https://ncbi.nlm.nih.gov/pubmed/31606248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.08.035
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