E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer

E-cadherin is a transmembrane glycoprotein responsible for cell-to-cell adhesion, and its loss has been associated with metastasis development. Although E-cadherin downregulation was previously reported in canine prostate cancer (PC), the mechanism involved in this process is unclear. It is well est...

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Publicat a:Front Genet
Autors principals: Fonseca-Alves, Carlos Eduardo, Kobayashi, Priscila Emiko, Leis-Filho, Antonio Fernando, Lainetti, Patricia de Faria, Grieco, Valeria, Kuasne, Hellen, Rogatto, Silvia Regina, Laufer-Amorim, Renee
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895247/
https://ncbi.nlm.nih.gov/pubmed/31850082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01242
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