Oxidative Stress Attenuates TLR3 Responsiveness and Impairs Anti-viral Mechanisms in Bronchial Epithelial Cells From COPD and Asthma Patients

COPD and asthma exacerbations are commonly triggered by rhinovirus infection. Potentially promoting exacerbations, impaired anti-viral signaling and attenuated viral clearance have been observed in diseased bronchial epithelium. Oxidative stress is a feature of inflammation in asthma and COPD and is...

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發表在:Front Immunol
Main Authors: Menzel, Mandy, Ramu, Sangeetha, Calvén, Jenny, Olejnicka, Beata, Sverrild, Asger, Porsbjerg, Celeste, Tufvesson, Ellen, Bjermer, Leif, Akbarshahi, Hamid, Uller, Lena
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895140/
https://ncbi.nlm.nih.gov/pubmed/31849956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02765
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