A Critical Role for Mucosal-Associated Invariant T Cells as Regulators and Therapeutic Targets in Systemic Lupus Erythematosus

Mucosal-associated invariant T (MAIT) cells are a subset of innate-like lymphocytes that are restricted by major histocompatibility complex-related molecule 1 (MR1). In this study, we investigated the role of MAIT cells in the pathogenesis of lupus in FcγRIIb(−/−)Yaa mice, a spontaneous animal model...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Murayama, Goh, Chiba, Asako, Suzuki, Hitoshi, Nomura, Atsushi, Mizuno, Tomohiro, Kuga, Taiga, Nakamura, Shinji, Amano, Hirofumi, Hirose, Sachiko, Yamaji, Ken, Suzuki, Yusuke, Tamura, Naoto, Miyake, Sachiko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895065/
https://ncbi.nlm.nih.gov/pubmed/31849932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02681
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