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Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism

A follicular spike in cyclic AMP (cAMP) and its subsequent degradation to AMP promotes oocyte maturation and ovulation. In vitro matured (IVM) oocytes do not receive the cAMP increase that occurs in vivo, and artificial elevation of cAMP in IVM cumulus-oocyte complexes improves oocyte developmental...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Richani, Dulama, Lavea, Cathy F., Kanakkaparambil, Raji, Riepsamen, Angelique H., Bertoldo, Michael J., Bustamante, Sonia, Gilchrist, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895058/
https://ncbi.nlm.nih.gov/pubmed/31804531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54693-y
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