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Epidermal growth factor receptor first generation tyrosine-kinase inhibitors

The epidermal growth factor receptor (EGFR) oncogene was positioned as an attractive target for drug development in non-small cell lung cancer (NSCLC). Gefitinib and erlotinib were the first two reversible inhibitors of the EGFR kinase. The discovery of EGFR kinase domain-activating mutations that s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Transl Lung Cancer Res
Main Authors: Martinez-Marti, Alex, Navarro, Alejandro, Felip, Enriqueta
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894987/
https://ncbi.nlm.nih.gov/pubmed/31857948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2019.04.20
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