Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation

It is becoming increasingly clear that brain network organization shapes the course and expression of neurodegenerative diseases. Parkinson disease (PD) is marked by progressive spread of atrophy from the midbrain to subcortical structures and, eventually, to the cerebral cortex. Recent discoveries...

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Udgivet i:PLoS Biol
Main Authors: Zheng, Ying-Qiu, Zhang, Yu, Yau, Yvonne, Zeighami, Yashar, Larcher, Kevin, Misic, Bratislav, Dagher, Alain
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894889/
https://ncbi.nlm.nih.gov/pubmed/31751329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000495
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