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Time-synchronized immune-guided SBRT partial bulky tumor irradiation targeting hypoxic segment while sparing the peritumoral immune microenvironment

BACKGROUND: A novel unconventional SBRT-based PArtial Tumor irradiation targeting HYpoxic clonogenic cells (SBRT-PATHY) for induction of the tumoricidal bystander (BE) and abscopal effects (AE) was developed by translating our preclinical findings to a clinic in 2016. In order to further improve BE/...

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Detalles Bibliográficos
Publicado en:Radiat Oncol
Autores principales: Tubin, Slavisa, Ashdown, Martin, Jeremic, Branislav
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894294/
https://ncbi.nlm.nih.gov/pubmed/31801549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-019-1423-9
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