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Xenofree generation of limbal stem cells for ocular surface advanced cell therapy

BACKGROUND: Limbal stem cells (LSC) sustain the corneal integrity and homeostasis. LSC deficiency (LSCD) leads to loss of corneal transparency and blindness. A clinical approach to treat unilateral LSCD comprises autologous cultured limbal epithelial stem cell transplantation (CLET). CLET uses xenob...

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Bibliografski detalji
Izdano u:Stem Cell Res Ther
Glavni autori: Nieto-Nicolau, Nuria, Martínez-Conesa, Eva M., Velasco-García, Alba M., Aloy-Reverté, Caterina, Vilarrodona, Anna, Casaroli-Marano, Ricardo P.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894225/
https://ncbi.nlm.nih.gov/pubmed/31801638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1501-9
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