Factors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening

BACKGROUND: The identification of cell-free fetal DNA (cffDNA) facilitated non-invasive prenatal screening (NIPS) through analysis of cffDNA in maternal plasma. However, challenges regarding its clinical implementation become apparent. Factors affecting fetal fraction should be clarified to guide it...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Hou, Yaping, Yang, Jiexia, Qi, Yiming, Guo, Fangfang, Peng, Haishan, Wang, Dongmei, Wang, Yixia, Luo, Xiaohui, Li, Yi, Yin, Aihua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894209/
https://ncbi.nlm.nih.gov/pubmed/31801621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0244-0
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