Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) is a prevalent spinal deformity occurring during peripubertal growth period that affects 1–4% of adolescents globally without clear etiopathogenetic mechanism. Low bone mineral density is an independent and significant prognostic factor for curve progression. Cu...

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Vydáno v:FASEB J
Hlavní autoři: Chen, Huanxiong, Zhang, Jiajun, Wang, Yujia, Cheuk, Ka-Yee, Hung, Alec L. H., Lam, Tsz-Ping, Qiu, Yong, Feng, Jian Q., Lee, Wayne Y. W., Cheng, Jack C. Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894095/
https://ncbi.nlm.nih.gov/pubmed/31626573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901227R
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