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Npro of Classical Swine Fever Virus Suppresses Type III Interferon Production by Inhibiting IRF1 Expression and Its Nuclear Translocation

Classical swine fever virus (CSFV) causes a contagious disease of pigs. The virus can break the mucosal barrier to establish its infection. Type III interferons (IFN-λs) play a crucial role in maintaining the antiviral state in epithelial cells. Limited information is available on whether or how CSF...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Cao, Tong, Li, Xiaoye, Xu, Yonghao, Zhang, Shengnan, Wang, Zuohuan, Shan, Ying, Sun, Jianhe, Fang, Weihuan, Li, Xiaoliang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893713/
https://ncbi.nlm.nih.gov/pubmed/31683525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11110998
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