Grape Seed Extract Eliminates Visceral Allodynia and Colonic Hyperpermeability Induced by Repeated Water Avoidance Stress in Rats

Grape seed extract (GSE) is rich in polyphenols composed mainly of proanthocyanidins, which are known to attenuate proinflammatory cytokine production. Repeated water avoidance stress (WAS) induces visceral allodynia and colonic hyperpermeability via toll-like receptor 4 (TLR4) and proinflammatory c...

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Bibliographic Details
Published in:Nutrients
Main Authors: Arie, Hideyuki, Nozu, Tsukasa, Miyagishi, Saori, Ida, Masayuki, Izumo, Takayuki, Shibata, Hiroshi
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893525/
https://ncbi.nlm.nih.gov/pubmed/31689935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11112646
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