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A nuclear licence to silence transposons

Transposon silencing requires the histone methyltransferase SETDB1. In this issue of EMBO Reports, Tsusaka et al [1] and Osumi et al [2] illustrate how the cofactor ATF7IP and its fly homolog Windei (Wde) regulate the methyltransferase function of SETDB1 through its nuclear licensing. The new insigh...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Gould, Poppy A, Rowe, Helen M
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893317/
https://ncbi.nlm.nih.gov/pubmed/31621182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949262
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