Optogenetic inhibition of Delta reveals digital Notch signalling output during tissue differentiation

Spatio‐temporal regulation of signalling pathways plays a key role in generating diverse responses during the development of multicellular organisms. The role of signal dynamics in transferring signalling information in vivo is incompletely understood. Here, we employ genome engineering in Drosophil...

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Vydáno v:EMBO Rep
Hlavní autoři: Viswanathan, Ranjith, Necakov, Aleksandar, Trylinski, Mateusz, Harish, Rohit Krishnan, Krueger, Daniel, Esposito, Emilia, Schweisguth, Francois, Neveu, Pierre, De Renzis, Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893285/
https://ncbi.nlm.nih.gov/pubmed/31668010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947999
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