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Natural Genetic Variation Screen in Drosophila Identifies Wnt Signaling, Mitochondrial Metabolism, and Redox Homeostasis Genes as Modifiers of Apoptosis

Apoptosis is the primary cause of degeneration in a number of neuronal, muscular, and metabolic disorders. These diseases are subject to a great deal of phenotypic heterogeneity in patient populations, primarily due to differences in genetic variation between individuals. This creates a barrier to e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Palu, Rebecca A. S., Ong, Elaine, Stevens, Kaitlyn, Chung, Shani, Owings, Katie G., Goodman, Alan G., Chow, Clement Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893197/
https://ncbi.nlm.nih.gov/pubmed/31570502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400722
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