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Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis

BACKGROUND: Bone morphogenetic proteins (BMPs) regulate adipogenesis but it is not clear whether they influence regional adipose tissue (AT) development in humans. OBJECTIVE: To characterise BMP2 expression, BMP2-SMAD1/5/8 signalling, and BMP2′s potential effect on proliferation and adipogenesis in...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Denton, Nathan F., Eghleilib, Mohamed, Al-Sharifi, Sama, Todorčević, Marijana, Neville, Matt J., Loh, Nellie, Drakesmith, Alexander, Karpe, Fredrik, Pinnick, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892741/
https://ncbi.nlm.nih.gov/pubmed/31324879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-019-0421-1
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