Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis

BACKGROUND AND AIM: Non-alcoholic steatohepatitis (NASH) is predicted to become the most common cause of cirrhosis and liver failure. Risk factors include obesity, insulin resistance and diabetes. Macrophages and other myeloid cells play crucial roles in initiating and driving inflammation. Aryl hyd...

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Veröffentlicht in:PLoS One
Hauptverfasser: Scott, Christopher, Stokes, Rebecca, Cha, Kuan Minn, Clouston, Andrew, Eslam, Mohammed, Metwally, Mayda, Swarbrick, Michael M., George, Jacob, Gunton, Jenny E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892561/
https://ncbi.nlm.nih.gov/pubmed/31800592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225332
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