Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis

BACKGROUND AND AIM: Non-alcoholic steatohepatitis (NASH) is predicted to become the most common cause of cirrhosis and liver failure. Risk factors include obesity, insulin resistance and diabetes. Macrophages and other myeloid cells play crucial roles in initiating and driving inflammation. Aryl hyd...

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Udgivet i:PLoS One
Main Authors: Scott, Christopher, Stokes, Rebecca, Cha, Kuan Minn, Clouston, Andrew, Eslam, Mohammed, Metwally, Mayda, Swarbrick, Michael M., George, Jacob, Gunton, Jenny E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892561/
https://ncbi.nlm.nih.gov/pubmed/31800592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225332
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