CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation

Through the progressive accumulation of genetic and epigenetic alterations in cellular physiology, non–small-cell lung cancer (NSCLC) evolves in distinct steps involving mutually exclusive oncogenic mutations in K-Ras or EGFR along with inactivating mutations in the p53 tumor suppressor. Herein, we...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Chavdoula, Evangelia, Habiel, David M, Roupakia, Eugenia, Markopoulos, Georgios S, Vasilaki, Eleni, Kokkalis, Antonis, Polyzos, Alexander P, Boleti, Haralabia, Thanos, Dimitris, Klinakis, Apostolos, Kolettas, Evangelos, Marcu, Kenneth B
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892436/
https://ncbi.nlm.nih.gov/pubmed/31792060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900460
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