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Silencing lncRNA ZFAS1 or elevated microRNA-135a represses proliferation, migration, invasion and resistance to apoptosis of osteosarcoma cells

BACKGROUND: Osteosarcoma (OS) is still a disease with high mortality from malignant tumors in children and adolescents. Due to its poor treatment, this study explored the involvement of lncRNA ZFAS1/microRNA-135a (miR-135a)/apurinic/apyrimidinic exonuclease 1 (APEX1) axis in the regulation of OS gro...

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Détails bibliographiques
Publié dans:Cancer Cell Int
Auteurs principaux: Zhao, Zilong, Lin, Xiafei, Tong, Yunhui, Li, Wenxia
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892223/
https://ncbi.nlm.nih.gov/pubmed/31827400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1049-x
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