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Genetics and functions of the retinoic acid pathway, with special emphasis on the eye

Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is essential for normal optic vesicle and anterior segment formation. Perturbation in RA-signaling...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Thompson, Brian, Katsanis, Nicholas, Apostolopoulos, Nicholas, Thompson, David C., Nebert, Daniel W., Vasiliou, Vasilis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892198/
https://ncbi.nlm.nih.gov/pubmed/31796115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0248-9
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