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Afann: bias adjustment for alignment-free sequence comparison based on sequencing data using neural network regression

Alignment-free methods, more time and memory efficient than alignment-based methods, have been widely used for comparing genome sequences or raw sequencing samples without assembly. However, in this study, we show that alignment-free dissimilarity calculated based on sequencing samples can be overes...

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Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Tang, Kujin, Ren, Jie, Sun, Fengzhu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891986/
https://ncbi.nlm.nih.gov/pubmed/31801606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1872-3
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