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The Dynamics of Hole Transfer in DNA

High-energy radiation and oxidizing agents can ionize DNA. One electron oxidation gives rise to a radical cation whose charge (hole) can migrate through DNA covering several hundreds of Å, eventually leading to irreversible oxidative damage and consequent disease. Understanding the thermodynamic, ki...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Peluso, Andrea, Caruso, Tonino, Landi, Alessandro, Capobianco, Amedeo
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891780/
https://ncbi.nlm.nih.gov/pubmed/31703470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224044
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