Kinetic Modelling of [(68)Ga]Ga-DOTA-Siglec-9 in Porcine Osteomyelitis and Soft Tissue Infections

Background: [(68)Ga]Ga-DOTA-Siglec-9 is a positron emission tomography (PET) radioligand for vascular adhesion protein 1 (VAP-1), a protein involved in leukocyte trafficking. The tracer facilitates the imaging of inflammation and infection. Here, we studied the pharmacokinetic modelling of [(68)Ga]G...

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Udgivet i:Molecules
Main Authors: Jødal, Lars, Roivainen, Anne, Oikonen, Vesa, Jalkanen, Sirpa, Hansen, Søren B., Afzelius, Pia, Alstrup, Aage K. O., Nielsen, Ole L., Jensen, Svend B.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891593/
https://ncbi.nlm.nih.gov/pubmed/31766140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224094
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