Design, Synthesis and Biological Evaluation of Diosgenin-Amino Acid Derivatives with Dual Functions of Neuroprotection and Angiogenesis

Diosgenin, a natural product with steroidal structure, has a wide range of clinical applications in China. It also shows great potential in the treatment of blood clots and nerve damage. To enhance the bioavailability as well as efficacy of diosgenin, eighteen diosgenin-amino acid derivatives were d...

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Bibliographic Details
Published in:Molecules
Main Authors: Cai, Desheng, Qi, Jinchai, Yang, Yuqin, Zhang, Wenxi, Zhou, Fei, Jia, Xiaohui, Guo, Wenbo, Huang, Xuemei, Gao, Feng, Chen, Hongshan, Li, Tong, Li, Guoping, Wang, Penglong, Zhang, Yuzhong, Lei, Haimin
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891328/
https://ncbi.nlm.nih.gov/pubmed/31703284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224025
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