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Distinct Roles for BET Family Members in Estrogen Receptor α Enhancer Function and Gene Regulation in Breast Cancer Cells
The bromodomain family member proteins (BRDs; BET proteins) are key coregulators for estrogen receptor alpha (ERα)-mediated transcriptional enhancers. The use of BRD selective inhibitors has gained much attention as a potential treatment for various solid tumors, including ER-positive breast cancers...
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| Vydáno v: | Mol Cancer Res |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891197/ https://ncbi.nlm.nih.gov/pubmed/31551256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0393 |
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