Short and long-term effects of CDK4/6 inhibition on early stage breast cancer

CDK4/6 inhibitors are used in the treatment of advanced estrogen receptor (ER)(+) breast cancer (BC). Their efficacy in ER(−) and early stage BC is currently under investigation. Here, we show that palbociclib, a CDK4/6 inhibitor, can inhibit both progression of ductal carcinoma in situ (DCIS) and g...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Kietzman, William B., Graham, Garrett T., Ory, Virginie, Sharif, Ghada, Kushner, Max H., Gallanis, Gregory T., Kallakury, Bhaskar, Wellstein, Anton, Riegel, Anna T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891167/
https://ncbi.nlm.nih.gov/pubmed/31451564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0231
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