NCS-1 Deficiency Affects mRNA Levels of Genes Involved in Regulation of ATP Synthesis and Mitochondrial Stress in Highly Vulnerable Substantia nigra Dopaminergic Neurons

Neuronal Ca(2+) sensor proteins (NCS) transduce changes in Ca(2+) homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration of dopaminergic (DA) neurons, particularly within the Substanti...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Simons, Carsten, Benkert, Julia, Deuter, Nora, Poetschke, Christina, Pongs, Olaf, Schneider, Toni, Duda, Johanna, Liss, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890851/
https://ncbi.nlm.nih.gov/pubmed/31827421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00252
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