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Exploiting Substrate Promiscuity of Ectoine Hydroxylase for Regio- and Stereoselective Modification of Homoectoine

Extant enzymes are not only highly efficient biocatalysts for a single, or a group of chemically closely related substrates but often have retained, as a mark of their evolutionary history, a certain degree of substrate ambiguity. We have exploited the substrate ambiguity of the ectoine hydroxylase...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Czech, Laura, Wilcken, Sarah, Czech, Oliver, Linne, Uwe, Brauner, Jarryd, Smits, Sander H. J., Galinski, Erwin A., Bremer, Erhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890836/
https://ncbi.nlm.nih.gov/pubmed/31827466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02745
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