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A new bioluminescence-based tool for modulating target proteins in live cells

We have developed a new genetically encoded tool designed to generate reactive oxygen species (ROS) at target proteins in cultured cells; it is designed using firefly luciferase and photosensitiser protein KillerRed. Targeting this fusion protein, KillerFirefly, to F-actin in live cells and treatmen...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ishimoto, Tetsuya, Mori, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890795/
https://ncbi.nlm.nih.gov/pubmed/31796796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54712-y
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