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Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies

Here we report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs. We first demonstrate that the binding of a specific antibody to a pair of antigen-conjugated split DNA input-strands induces their co-loc...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ranallo, Simona, Sorrentino, Daniela, Ricci, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890650/
https://ncbi.nlm.nih.gov/pubmed/31796740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13104-6
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