Genomic Profiling Reveals Synchronous Bilateral Lung Adenocarcinomas With Distinct Driver Alterations of EML4-ALK or TPM3-ROS1 Fusion: A Case Report

Background: ALK and ROS1 rearrangement accounts for 3–6% and 1–3% of non-small cell lung cancers, respectively, while coexistence of them in the same patient is extremely rare. Only three cases have ever been reported with concurrent ALK/ROS1 fusions in the same tumor indicating tumor heterogeneity....

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Asıl Yazarlar: Tan, Benxu, Jiang, Xuan, Wang, Ruping, Tang, Cuiping, Liu, Sisi, Wu, Xue, Xia, Lei, Yu, Xian, Yang, Zhenzhou
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Oncology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890554/
https://ncbi.nlm.nih.gov/pubmed/31828041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01319
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