Analysis of stochastic fluctuations in responsiveness is a critical step toward personalized anesthesia

Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here, we interrogate the relationship between population-based and individu...

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Bibliographic Details
Published in:eLife
Main Authors: McKinstry-Wu, Andrew R, Wasilczuk, Andrzej Z, Harrison, Benjamin A, Bedell, Victoria M, Sridharan, Mathangi J, Breig, Jayce J, Pack, Michael, Kelz, Max B, Proekt, Alexander
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890463/
https://ncbi.nlm.nih.gov/pubmed/31793434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50143
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