Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

For neural systems to function effectively, the numbers of each cell type must be proportioned properly during development. We found that conditional knockout of the mouse homeobox genes En1 and En2 in the excitatory cerebellar nuclei neurons (eCN) leads to reduced postnatal growth of the cerebellar...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Willett, Ryan T, Bayin, N Sumru, Lee, Andrew S, Krishnamurthy, Anjana, Wojcinski, Alexandre, Lao, Zhimin, Stephen, Daniel, Rosello-Diez, Alberto, Dauber-Decker, Katherine L, Orvis, Grant D, Wu, Zhuhao, Tessier-Lavigne, Marc, Joyner, Alexandra L
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890462/
https://ncbi.nlm.nih.gov/pubmed/31742552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50617
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