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Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis

BACKGROUND: Prostate cancer (Pca) remains one of the leading adult malignancies. PTEN (Phosphatase and Tensin Homolog) mutant is the top common mutated genes in prostate cancer, which makes it a promising biomarker in future individualized treatment. METHODS: We obtained gene expression data of pros...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Sun, Jian, Li, Shugen, Wang, Fei, Fan, Caibin, Wang, Jianqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889628/
https://ncbi.nlm.nih.gov/pubmed/31791268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0923-7
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