Loss of Pancreatic E-Cadherin Causes Pancreatitis-Like Changes and Contributes to Carcinogenesis

BACKGROUND & AIMS: E-cadherin (Cdh1) is a key molecule for adherence required for maintenance of structural homeostasis. Loss of E-cadherin leads to poor prognosis and the development of resistance to chemotherapy in pancreatic cancer. Here, we evaluated the physiological and pathologic roles of...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Kaneta, Yoshihiro, Sato, Takeshi, Hikiba, Yohko, Sugimori, Makoto, Sue, Soichiro, Kaneko, Hiroaki, Irie, Kuniyasu, Sasaki, Tomohiko, Kondo, Masaaki, Chuma, Makoto, Shibata, Wataru, Maeda, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889596/
https://ncbi.nlm.nih.gov/pubmed/31526907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.09.001
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