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In order for the light to shine so brightly, the darkness must be present—why do cancers fluoresce with 5-aminolaevulinic acid?

Photodynamic diagnosis and therapy have emerged as a promising tool in oncology. Using the visible fluorescence from photosensitisers excited by light, clinicians can both identify and treat tumour cells in situ. Protoporphyrin IX, produced in the penultimate step of the haem synthesis pathway, is a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: McNicholas, Kym, MacGregor, Melanie N., Gleadle, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889380/
https://ncbi.nlm.nih.gov/pubmed/31406300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0516-4
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