Thawed Mesenchymal Stem Cell Product Shows Comparable Immunomodulatory Potency to Cultured Cells In Vitro and in Polymicrobial Septic Animals

Mesenchymal stem cells (MSCs) have been shown to exert immunomodulatory effects in both acute and chronic diseases. In acute inflammatory conditions like sepsis, cell therapy must be administered within hours of diagnosis, requiring “off-the-shelf” cryopreserved allogeneic cell products. However, th...

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Publicado no:Sci Rep
Main Authors: Tan, Yuan, Salkhordeh, Mahmoud, Wang, Jia-Pey, McRae, Andrea, Souza-Moreira, Luciana, McIntyre, Lauralyn, Stewart, Duncan J., Mei, Shirley H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889371/
https://ncbi.nlm.nih.gov/pubmed/31792313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54462-x
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