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The Effect of pH on Antibiotic Efficacy against Coxiella burnetii in Axenic Media

Coxiella burnetii, the etiologic agent of Q fever, replicates in an intracellular phagolysosome with pH between 4 and 5. The impact of this low pH environment on antimicrobial treatment is not well understood. An in vitro system for testing antibiotic susceptibility of C. burnetii in axenic media wa...

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Foilsithe in:Sci Rep
Main Authors: Smith, Cody B., Evavold, Charles, Kersh, Gilbert J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889355/
https://ncbi.nlm.nih.gov/pubmed/31792307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54556-6
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