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Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer
Osimertinib is an irreversible, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that is highly selective for EGFR-activating mutations as well as the EGFR T790M mutation in patients with advanced non-small cell lung cancer (NSCLC) with EGFR oncogene addiction. Desp...
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| Pubblicato in: | Br J Cancer |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6889286/ https://ncbi.nlm.nih.gov/pubmed/31564718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0573-8 |
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