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Reducing Viral Inhibition of Host Cellular Apoptosis Strengthens the Immunogenicity and Protective Efficacy of an Attenuated HSV-1 Strain

Herpes simplex virus 1 (HSV-1), a member of α herpesviruses, shows a high infectivity rate of 30%–60% in populations of various ages. Some herpes simplex (HSV) vaccine candidates evaluated during the past 20 years have not shown protective efficacy against viral infection. An improved understanding...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Xu, Xingli, He, Yufeng, Fan, Shengtao, Feng, Min, Jiang, Guorun, Wang, Lichun, Zhang, Ying, Liao, Yun, Li, Qihan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889118/
https://ncbi.nlm.nih.gov/pubmed/31506828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-019-00156-7
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