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Gene fusions and chimeric RNAs, and their implications in cancer

Gene fusions are appreciated as ideal cancer biomarkers and therapeutic targets. Chimeric RNAs are traditionally thought to be products of gene fusions, and thus, also cancer-specific. Recent research has demonstrated that chimeric RNAs can be generated by intergenic splicing in the absence of gene...

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Wu, Hao, Li, Xiaorong, Li, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889028/
https://ncbi.nlm.nih.gov/pubmed/31832518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.08.002
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