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Gene fusions and chimeric RNAs, and their implications in cancer

Gene fusions are appreciated as ideal cancer biomarkers and therapeutic targets. Chimeric RNAs are traditionally thought to be products of gene fusions, and thus, also cancer-specific. Recent research has demonstrated that chimeric RNAs can be generated by intergenic splicing in the absence of gene...

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Détails bibliographiques
Publié dans:Genes Dis
Auteurs principaux: Wu, Hao, Li, Xiaorong, Li, Hui
Format: Artigo
Langue:Inglês
Publié: Chongqing Medical University 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889028/
https://ncbi.nlm.nih.gov/pubmed/31832518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.08.002
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