SPATIAL GENOME EXPLORATION IN THE CONTEXT OF COGNITIVE AND NEUROLOGICAL DISEASE

The ‘non-linear’ genome, or the spatial proximity of non-contiguous sequences, emerges as an important regulatory layer for genome organization and function, including transcriptional regulation. Here, we review recent genome-scale chromosome conformation mappings (‘Hi-C’) in developing and adult hu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin Neurobiol
Prif Awduron: Rajarajan, Prashanth, Borrman, Tyler, Liao, Will, Gil, Sergio Espeso, Chandrasekaran, Sandhya, Jiang, Yan, Weng, Zhiping, Brennand, Kristen J., Akbarian, Schahram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889018/
https://ncbi.nlm.nih.gov/pubmed/31255842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2019.05.007
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