Prostaglandin F(2α)-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity

The role of prostaglandin (PG) F(2α) has been scarcely studied in cancer. We have identified a new function for PGF(2α) in ovarian cancer, stimulating the production of Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1). We show that this induction increases cell plasticity and proliferatio...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Jiménez-Segovia, Alba, Mota, Alba, Rojo-Sebastián, Alejandro, Barrocal, Beatriz, Rynne-Vidal, Angela, García-Bermejo, María-Laura, Gómez-Bris, Raquel, Hawinkels, Lukas J.A.C., Sandoval, Pilar, Garcia-Escudero, Ramon, López-Cabrera, Manuel, Moreno-Bueno, Gema, Fresno, Manuel, Stamatakis, Konstantinos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2019
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888713/
https://ncbi.nlm.nih.gov/pubmed/31734628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.10.001
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