Pyruvate Dehydrogenase and Tricarboxylic Acid Cycle Enzymes Are Sensitive Targets of Traumatic Brain Injury Induced Metabolic Derangement

Using a closed-head impact acceleration model of mild or severe traumatic brain injury (mTBI or sTBI, respectively) in rats, we evaluated the effects of graded head impacts on the gene and protein expressions of pyruvate dehydrogenase (PDH), as well as major enzymes of mitochondrial tricarboxylic ac...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lazzarino, Giacomo, Amorini, Angela Maria, Signoretti, Stefano, Musumeci, Giuseppe, Lazzarino, Giuseppe, Caruso, Giuseppe, Pastore, Francesco Saverio, Di Pietro, Valentina, Tavazzi, Barbara, Belli, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888669/
https://ncbi.nlm.nih.gov/pubmed/31744143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225774
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