LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis

Hematopoietic transcription factor LIM domain only 2 (LMO2), a member of the TAL1 transcriptional complex, plays an essential role during early hematopoiesis and is frequently activated in T-cell acute lymphoblastic leukemia (T-ALL) patients. Here, we demonstrate that LMO2 is activated by deacetylat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Morishima, Tatsuya, Krahl, Ann-Christin, Nasri, Masoud, Xu, Yun, Aghaallaei, Narges, Findik, Betül, Klimiankou, Maksim, Ritter, Malte, Hartmann, Marcus D., Gloeckner, Christian Johannes, Stefanczyk, Sylwia, Lindner, Christian, Oswald, Benedikt, Bernhard, Regine, Hähnel, Karin, Hermanutz-Klein, Ursula, Ebinger, Martin, Handgretinger, Rupert, Casadei, Nicolas, Welte, Karl, Andre, Maya, Müller, Patrick, Bajoghli, Baubak, Skokowa, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888148/
https://ncbi.nlm.nih.gov/pubmed/31366618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000095
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados